A robust TDP-43 knock-in mouse model of ALS

Amyotrophic lateral sclerosis (ALS) is a fatal, adult-onset degenerative disorder of motor neurons. The diseased spinal cord motor neurons of more than 95% of amyotrophic lateral sclerosis (ALS) patients are characterized by the mis-metabolism of the RNA/DNA-binding protein TDP-43 (ALS-TDP), in part...

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Detalles Bibliográficos
Autores principales: Huang, Shih-Ling, Wu, Lien-Szu, Lee, Min, Chang, Chin-Wen, Cheng, Wei-Cheng, Fang, Yu-Sheng, Chen, Yun-Ru, Cheng, Pei-Lin, Shen, Che-Kun James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975031/
https://www.ncbi.nlm.nih.gov/pubmed/31964415
http://dx.doi.org/10.1186/s40478-020-0881-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975031/
https://www.ncbi.nlm.nih.gov/pubmed/31964415
http://dx.doi.org/10.1186/s40478-020-0881-5

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