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Comprehensive molecular characterization of inhibitors of apoptosis proteins (IAPs) for therapeutic targeting in cancer

BACKGROUND: Inhibitors of apoptosis proteins (IAPs) are a family of antiapoptotic proteins modulating cell cycle, signal transduction and apoptosis. Dysregulated IAPs have been reported to contribute to tumor progression and chemoresistance in various cancers. However, existing studies were sporadic...

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Detalles Bibliográficos
Autores principales: Liang, Jianfeng, Zhao, Wanni, Tong, Pan, Li, Ping, Zhao, Yuanli, Li, Hua, Liang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975060/
https://www.ncbi.nlm.nih.gov/pubmed/31964418
http://dx.doi.org/10.1186/s12920-020-0661-x

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