Cargando…

Integrated Plasma and Bile Metabolomics Based on an UHPLC-Q/TOF-MS and Network Pharmacology Approach to Explore the Potential Mechanism of Schisandra chinensis-Protection From Acute Alcoholic Liver Injury

Schisandra chinensis (SC) is a well-known important traditional Chinese medicine (TCM) that has been used to treat liver disease in China for a long time. However, its overall effects and mechanism of action are unclear. The present study aimed to explore the potential mechanism of SC in protection...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Lianlin, Mao, Jing, Hao, Min, Lu, Tulin, Mao, Chunqin, Ji, De, Tong, Huangjin, Fei, Chenghao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975200/ https://www.ncbi.nlm.nih.gov/pubmed/32009955 http://dx.doi.org/10.3389/fphar.2019.01543

Ejemplares similares

The Anti-colitis Effect of Schisandra chinensis Polysaccharide Is Associated With the Regulation of the Composition and Metabolism of Gut Microbiota
por: Su, Lianlin, et al.
Publicado: (2020)

Mechanism of Curcuma wenyujin Rhizoma on Acute Blood Stasis in Rats Based on a UPLC-Q/TOF-MS Metabolomics and Network Approach
por: Hao, Min, et al.
Publicado: (2018)

Simultaneous determination of eleven characteristic lignans in Schisandra chinensis by high-performance liquid chromatography
por: Hu, Junyang, et al.
Publicado: (2013)

Therapeutic mechanism of Curcuma aromatica Salisb. rhizome against coronary heart disease based on integrated network pharmacology, pharmacological evaluation and lipidomics
por: Fei, Chenghao, et al.
Publicado: (2022)

Revealing the mechanism of raw and vinegar-processed Curcuma aromatica Salisb. [Zingiberaceae] regulates primary dysmenorrhea in rats via integrated metabolomics
por: Su, Lianlin, et al.
Publicado: (2022)

Rapid Classification and Identification of Chemical Components of Schisandra Chinensis by UPLC-Q-TOF/MS Combined with Data Post-Processing
por: Yang, Shenshen, et al.
Publicado: (2017)

Mechanisms Underlying the Action of Ziziphi Spinosae Semen in the Treatment of Insomnia: A Study Involving Network Pharmacology and Experimental Validation
por: Bian, Zhenhua, et al.
Publicado: (2021)

Untargeted Metabolomics of Fermented Rice Using UHPLC Q-TOF MS/MS Reveals an Abundance of Potential Antihypertensive Compounds
por: Daliri, Eric Banan-Mwine, et al.
Publicado: (2020)

Systematically Characterize the Anti-Alzheimer’s Disease Mechanism of Lignans from S. chinensis Based on In-Vivo Ingredient Analysis and Target-Network Pharmacology Strategy by UHPLC–Q-TOF-MS
por: Wei, Mengying, et al.
Publicado: (2019)

Pharmacokinetics and Metabolism Study of Deep-Sea-Derived Butyrolactone I in Rats by UHPLC–MS/MS and UHPLC–Q-TOF-MS
por: Wu, Liang, et al.
Publicado: (2021)

Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS
por: Dong, Yaqian, et al.
Publicado: (2021)

Identification of Metabolites of Eupatorin in Vivo and in Vitro Based on UHPLC-Q-TOF-MS/MS
por: Li, Luya, et al.
Publicado: (2019)

Chemical Discrimination of Astragalus mongholicus and Astragalus membranaceus Based on Metabolomics Using UHPLC-ESI-Q-TOF-MS/MS Approach
por: Wang, Yumei, et al.
Publicado: (2019)

Untargeted Metabolomics Analysis Using UHPLC-Q-TOF/MS Reveals Metabolic Changes Associated with Hypertension in Children
por: Zhang, Kexin, et al.
Publicado: (2023)

UHPLC-Q-TOF-MS/MS and Network Pharmacology Analysis to Reveal Quality Markers of Xinjiang Cydonia oblonga Mill. for Antiatherosclerosis
por: Simayi, Jimilihan, et al.
Publicado: (2022)

Rapid Identification of Berberine Metabolites in Rat Plasma by UHPLC-Q-TOF-MS
por: Xu, Peng, et al.
Publicado: (2019)

Metabolite Profiling of Meridianin C In Vivo of Rat by UHPLC/Q-TOF MS
por: Zhang, Guozhe, et al.
Publicado: (2021)

Exploratory metabolomic analysis based on UHPLC-Q-TOF-MS/MS to study hypoxia-reoxygenation energy metabolic alterations in HK-2 cells
por: Yang, Xiaoyu, et al.
Publicado: (2023)

UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam
por: Pham, Hong Ngoc, et al.
Publicado: (2022)

On-line identification of the chemical constituents of Polygoni Multiflori Radix by UHPLC-Q-ToF MS/MS
por: Wang, Xueting, et al.
Publicado: (2023)

Filtration of Active Components with Antioxidant Activity Based on the Differing Antioxidant Abilities of Schisandrae Sphenantherae Fructus and Schisandrae Chinensis Fructus through UPLC/MS Coupling with Network Pharmacology
por: Xin, Yang, et al.
Publicado: (2021)

RNA-Seq and UHPLC-Q-TOF/MS Based Lipidomics Study in Lysiphlebia japonica
por: Gao, Xueke, et al.
Publicado: (2018)

Analysis of In Vivo Existence Forms of Nardosinone in Mice by UHPLC-Q-TOF-MS Technique
por: Zhang, Jing, et al.
Publicado: (2022)

Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS
por: He, Yan, et al.
Publicado: (2022)

The Impact of GFP Reporter Gene Transduction and Expression on Metabolomics of Placental Mesenchymal Stem Cells Determined by UHPLC-Q/TOF-MS
por: Yang, Jinfeng, et al.
Publicado: (2017)

UHPLC-Q-TOF/MS-Based Metabolomics Approach Reveals the Antifungal Potential of Pinocembroside against Citrus Green Mold Phytopathogen
por: Chen, Chuying, et al.
Publicado: (2019)

A comparative UHPLC-Q/TOF–MS-based eco-metabolomics approach reveals temperature adaptation of four Nepenthes species
por: Wong, Changi, et al.
Publicado: (2020)

Biomarkers and Mechanism Analysis for Polygoni Multiflori Radix Preparata-Induced Liver Injury by UHPLC-Q-TOF-MS-Based Metabolomics
por: Wang, Liming, et al.
Publicado: (2021)

Untargeted Metabolomics Pilot Study Using UHPLC-qTOF MS Profile in Sows’ Urine Reveals Metabolites of Bladder Inflammation
por: Pousinis, Petros, et al.
Publicado: (2022)

Comparative pharmacokinetic analysis of raw and steamed Panax notoginseng roots in rats by UPLC-MS/MS for simultaneously quantifying seven saponins
por: Dong, Jiajia, et al.
Publicado: (2021)

Network pharmacology-based study on the mechanism of Schisandra chinensis for treating Alzheimer's disease
por: Kun, Cheng, et al.
Publicado: (2020)

Identification and Pharmacokinetic Studies on Complanatuside and Its Major Metabolites in Rats by UHPLC-Q-TOF-MS/MS and LC-MS/MS
por: Yao, Yu-Feng, et al.
Publicado: (2018)

Screening and Identification of the Main Metabolites of Schisantherin a In Vivo and In Vitro by Using UHPLC-Q-TOF-MS/MS
por: Feng, Wei, et al.
Publicado: (2020)

Metabolite Identification of Isopropoxy Benzene Guanidine in Rat Liver Microsomes by Using UHPLC-Q-TOF-MS/MS
por: Lu, Yixing, et al.
Publicado: (2023)

Metabolomic signatures for liver tissue and cecum contents in high-fat diet-induced obese mice based on UHPLC-Q-TOF/MS
por: Cai, Hongying, et al.
Publicado: (2021)

Cell metabolomics study on the anticancer effects of Ophiopogon japonicus against lung cancer cells using UHPLC/Q-TOF-MS analysis
por: Liu, Qiao, et al.
Publicado: (2022)

Screening of metabolic markers present in Oxytropis by UHPLC-Q-TOF/MS and preliminary pharmacophylogenetic investigation
por: Jia, Xin, et al.
Publicado: (2022)

Identification for metabolism profiles and pharmacokinetic studies of tradition Chinese prescription Ji-Ming-San and its major metabolites in rats by UHPLC-Q-TOF-MS/MS and UHPLC-MS/MS
por: Hsieh, Cheng-Yang, et al.
Publicado: (2023)

Metabolomics study of the therapeutic mechanism of Schisandra Chinensis lignans in diet-induced hyperlipidemia mice
por: Sun, Jing-Hui, et al.
Publicado: (2017)

Untargeted Metabolomics of Korean Fermented Brown Rice Using UHPLC Q-TOF MS/MS Reveal an Abundance of Potential Dietary Antioxidative and Stress-Reducing Compounds
por: Tyagi, Akanksha, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_p7cp5f937eicaaq8nt4knepolc