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Malignant Thyroid-type Papillary Neoplasm in Struma Ovarii: A Case Report

Papillary thyroid carcinoma (PTC) arising in a coexistent struma ovarii (SO) is a rare malignancy. It manifests with abdominal symptoms such as palpable mass, pain, distension, and possibly ascites. It is usually diagnosed postoperatively, and its histopathological diagnostic criteria remain identic...

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Autores principales: Hassan, Syed Adeel, Akhtar, Ali, Falah, Noor Ul, Sheikh, Fahad N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975244/
https://www.ncbi.nlm.nih.gov/pubmed/32010534
http://dx.doi.org/10.7759/cureus.6450
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author Hassan, Syed Adeel
Akhtar, Ali
Falah, Noor Ul
Sheikh, Fahad N
author_facet Hassan, Syed Adeel
Akhtar, Ali
Falah, Noor Ul
Sheikh, Fahad N
author_sort Hassan, Syed Adeel
collection PubMed
description Papillary thyroid carcinoma (PTC) arising in a coexistent struma ovarii (SO) is a rare malignancy. It manifests with abdominal symptoms such as palpable mass, pain, distension, and possibly ascites. It is usually diagnosed postoperatively, and its histopathological diagnostic criteria remain identical to that of papillary carcinoma of the thyroid gland. Due to the relative rarity of the disease, definitive guidelines for its overall management are still undefined. We present a case of a 51-year old female with suspicion of a left ovarian tumor due to her presenting symptoms: raised serum CA-125 levels and abnormal abdominopelvic CT scan findings. She underwent complete surgical debulking of the mass (total abdominal hysterectomy (TAH), bilateral salpingo-oophorectomy (BSO), omentectomy, appendectomy, and pelvic lymphadenectomy). The mass was postoperatively diagnosed by histopathology as PTC in SO (stage IA). Furthermore, our patient did not receive any adjuvant treatment. The patient has been disease-free for 24 months post-surgery and is scheduled for regular biannual follow-ups.
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spelling pubmed-69752442020-01-31 Malignant Thyroid-type Papillary Neoplasm in Struma Ovarii: A Case Report Hassan, Syed Adeel Akhtar, Ali Falah, Noor Ul Sheikh, Fahad N Cureus Oncology Papillary thyroid carcinoma (PTC) arising in a coexistent struma ovarii (SO) is a rare malignancy. It manifests with abdominal symptoms such as palpable mass, pain, distension, and possibly ascites. It is usually diagnosed postoperatively, and its histopathological diagnostic criteria remain identical to that of papillary carcinoma of the thyroid gland. Due to the relative rarity of the disease, definitive guidelines for its overall management are still undefined. We present a case of a 51-year old female with suspicion of a left ovarian tumor due to her presenting symptoms: raised serum CA-125 levels and abnormal abdominopelvic CT scan findings. She underwent complete surgical debulking of the mass (total abdominal hysterectomy (TAH), bilateral salpingo-oophorectomy (BSO), omentectomy, appendectomy, and pelvic lymphadenectomy). The mass was postoperatively diagnosed by histopathology as PTC in SO (stage IA). Furthermore, our patient did not receive any adjuvant treatment. The patient has been disease-free for 24 months post-surgery and is scheduled for regular biannual follow-ups. Cureus 2019-12-23 /pmc/articles/PMC6975244/ /pubmed/32010534 http://dx.doi.org/10.7759/cureus.6450 Text en Copyright © 2019, Hassan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Hassan, Syed Adeel
Akhtar, Ali
Falah, Noor Ul
Sheikh, Fahad N
Malignant Thyroid-type Papillary Neoplasm in Struma Ovarii: A Case Report
title Malignant Thyroid-type Papillary Neoplasm in Struma Ovarii: A Case Report
title_full Malignant Thyroid-type Papillary Neoplasm in Struma Ovarii: A Case Report
title_fullStr Malignant Thyroid-type Papillary Neoplasm in Struma Ovarii: A Case Report
title_full_unstemmed Malignant Thyroid-type Papillary Neoplasm in Struma Ovarii: A Case Report
title_short Malignant Thyroid-type Papillary Neoplasm in Struma Ovarii: A Case Report
title_sort malignant thyroid-type papillary neoplasm in struma ovarii: a case report
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975244/
https://www.ncbi.nlm.nih.gov/pubmed/32010534
http://dx.doi.org/10.7759/cureus.6450
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