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Free energy profile for unwrapping outer superhelical turn of CENP-A nucleosome

Eukaryotic genome is packaged in a nucleus in the form of chromatin. The fundamental structural unit of the chromatin is the protein-DNA complex, nucleosome, where DNA of about 150 bp is wrapped around a histone core almost twice. In cellular processes such as gene expression, DNA repair and duplica...

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Detalles Bibliográficos
Autores principales: Kono, Hidetoshi, Sakuraba, Shun, Ishida, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975924/
https://www.ncbi.nlm.nih.gov/pubmed/31984189
http://dx.doi.org/10.2142/biophysico.16.0_337