Cargando…
High-risk blastemal Wilms tumor can be modeled by 3D spheroid cultures in vitro
In vitro models represent a critical tool in cancer research to study tumor biology and to evaluate new treatment options. Unfortunately, there are no effective preclinical models available that represent Wilms tumor (WT) — the most common pediatric renal tumor. Especially the high-risk blastemal WT...
Autores principales: | Wegert, Jenny, Zauter, Lisa, Appenzeller, Silke, Otto, Christoph, Bausenwein, Sabrina, Vokuhl, Christian, Ernestus, Karen, Furtwängler, Rhoikos, Graf, Norbert, Gessler, Manfred |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976522/ https://www.ncbi.nlm.nih.gov/pubmed/31562394 http://dx.doi.org/10.1038/s41388-019-1027-8 |
Ejemplares similares
-
TP53 alterations in Wilms tumour represent progression events with strong intratumour heterogeneity that are closely linked but not limited to anaplasia
por: Wegert, Jenny, et al.
Publicado: (2017) -
MYCN and MAX alterations in Wilms tumor and identification of novel N-MYC interaction partners as biomarker candidates
por: Jiménez Martín, Ovidio, et al.
Publicado: (2021) -
Retinoic acid pathway activity in wilms tumors and characterization of biological responses in vitro
por: Wegert, Jenny, et al.
Publicado: (2011) -
Vena Cava Thrombus in Patients with Wilms Tumor
por: Meier, Clemens-Magnus, et al.
Publicado: (2022) -
Impact of Time to Surgery on Outcome in Wilms Tumor Treated with Preoperative Chemotherapy
por: Meier, Clemens-Magnus, et al.
Publicado: (2023)