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Pimozide Inhibits the Human Prostate Cancer Cells Through the Generation of Reactive Oxygen Species

The United States Food and Drug Administration-approved antipsychotic drug, pimozide, has anticancer activities. However, the role of reactive oxygen species (ROS) in its effect on prostate cancer is not well-known. We examined cell proliferation, colony formation, migration, ROS production, and the...

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Detalles Bibliográficos
Autores principales: Kim, Ukjin, Kim, C-Yoon, Lee, Ji Min, Ryu, Bokyeong, Kim, Jin, Shin, Changsoo, Park, Jae-Hak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976539/
https://www.ncbi.nlm.nih.gov/pubmed/32009948
http://dx.doi.org/10.3389/fphar.2019.01517