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Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer

Trastuzumab is commonly used in the treatment of human epidermal growth factor receptor-2 positive (HER-2+) breast cancer, but its efficacy is often limited by the emergence of chemoresistance. Recent studies indicate that exosomes act as vehicles for exchange of genetic cargo between heterogeneous...

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Detalles Bibliográficos
Autores principales: Han, Mingli, Hu, Jianguo, Lu, Pengwei, Cao, Hui, Yu, Chao, Li, Xiangke, Qian, Xueke, Yang, Xue, Yang, Yunqing, Han, Na, Dou, Dongwei, Zhang, Fan, Ye, Mulin, Yang, Changcheng, Gu, Yuanting, Dong, Huaying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976584/
https://www.ncbi.nlm.nih.gov/pubmed/31969559
http://dx.doi.org/10.1038/s41419-020-2250-5