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Blockade of IL-6 signaling prevents paclitaxel-induced neuropathy in C57Bl/6 mice
The microtubule-stabilizing agent paclitaxel frequently leads to chemotherapy-induced peripheral neuropathy (CIN), which further increases the burden of disease and often necessitates treatment limitations. The pathophysiology of CIN appears to involve both “upstream” effects including altered intra...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976596/ https://www.ncbi.nlm.nih.gov/pubmed/31969555 http://dx.doi.org/10.1038/s41419-020-2239-0 |