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Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits
In the developing spinal cord, Onecut transcription factors control the diversification of motor neurons into distinct neuronal subsets by ensuring the maintenance of Isl1 expression during differentiation. However, other genes downstream of the Onecut proteins and involved in motor neuron diversifi...
Autores principales: | Toch, Mathilde, Harris, Audrey, Schakman, Olivier, Kondratskaya, Elena, Boulland, Jean-Luc, Dauguet, Nicolas, Debrulle, Stéphanie, Baudouin, Charlotte, Hidalgo-Figueroa, Maria, Mu, Xiuqian, Gow, Alexander, Glover, Joel C., Tissir, Fadel, Clotman, Frédéric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976625/ https://www.ncbi.nlm.nih.gov/pubmed/31969659 http://dx.doi.org/10.1038/s41598-020-57945-4 |
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