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Environmental arginine controls multinuclear giant cell metabolism and formation
Multinucleated giant cells (MGCs) are implicated in many diseases including schistosomiasis, sarcoidosis and arthritis. MGC generation is energy intensive to enforce membrane fusion and cytoplasmic expansion. Using receptor activator of nuclear factor kappa-Β ligand (RANKL) induced osteoclastogenesi...
Autores principales: | Brunner, Julia S., Vulliard, Loan, Hofmann, Melanie, Kieler, Markus, Lercher, Alexander, Vogel, Andrea, Russier, Marion, Brüggenthies, Johanna B., Kerndl, Martina, Saferding, Victoria, Niederreiter, Birgit, Junza, Alexandra, Frauenstein, Annika, Scholtysek, Carina, Mikami, Yohei, Klavins, Kristaps, Krönke, Gerhard, Bergthaler, Andreas, O’Shea, John J., Weichhart, Thomas, Meissner, Felix, Smolen, Josef S., Cheng, Paul, Yanes, Oscar, Menche, Jörg, Murray, Peter J., Sharif, Omar, Blüml, Stephan, Schabbauer, Gernot |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976629/ https://www.ncbi.nlm.nih.gov/pubmed/31969567 http://dx.doi.org/10.1038/s41467-020-14285-1 |
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