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Effects of microtubule-inhibiting small molecule and antibody-drug conjugate treatment on differentially-sized A431 squamous carcinoma spheroids

Multicellular tumor spheroids have been increasingly used by researchers to produce more physiologically relevant experimental environments. However, tracking of spheroid growth and treatment-induced volume reduction has not been readily adopted. Here, squamous carcinoma cells were seeded at differe...

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Detalles Bibliográficos
Autores principales: Durbin, Kenneth R., Nottoli, M. Shannon, Jenkins, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976639/
https://www.ncbi.nlm.nih.gov/pubmed/31969631
http://dx.doi.org/10.1038/s41598-020-57789-y