Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis–associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects

Nonalcoholic steatohepatitis (NASH) is a hepatic phenotype of the metabolic syndrome, and increases the risk of cirrhosis and hepatocellular carcinoma (HCC). Although increasing evidence points to the therapeutic implications of certain types of anti-diabetic agents in NASH, it remains to be elucida...

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Detalles Bibliográficos
Autores principales: Kawakubo, Mitsuhiro, Tanaka, Miyako, Ochi, Kozue, Watanabe, Akiko, Saka-Tanaka, Marie, Kanamori, Yohei, Yoshioka, Naoki, Yamashita, Satoko, Goto, Moritaka, Itoh, Michiko, Shirakawa, Ibuki, Kanai, Sayaka, Suzuki, Hiromi, Sawada, Makoto, Ito, Ayaka, Ishigami, Masatoshi, Fujishiro, Mitsuhiro, Arima, Hiroshi, Ogawa, Yoshihiro, Suganami, Takayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976646/
https://www.ncbi.nlm.nih.gov/pubmed/31969650
http://dx.doi.org/10.1038/s41598-020-57935-6

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