Behavioral characterization of a CRISPR-generated TRPA1 knockout rat in models of pain, itch, and asthma

The transient receptor potential (TRP) superfamily of ion channels has garnered significant attention by the pharmaceutical industry. In particular, TRP channels showing high levels of expression in sensory neurons such as TRPV1, TRPA1, and TRPM8, have been considered as targets for indications wher...

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Detalles Bibliográficos
Autores principales: Reese, Rebecca M., Dourado, Michelle, Anderson, Keith, Warming, Søren, Stark, Kimberly L., Balestrini, Alessia, Suto, Eric, Lee, Wyne, Riol-Blanco, Lorena, Shields, Shannon D., Hackos, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976688/
https://www.ncbi.nlm.nih.gov/pubmed/31969645
http://dx.doi.org/10.1038/s41598-020-57936-5

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