Cargando…

PIK3CA and PTEN Genes Expressions in Breast Cancer

BACKGROUND: The phosphatidylinositol-3 kinase (PI3K) intracellular signaling pathway plays an important role in breast cancer. The current study aimed to evaluate the expressions of two main regulators of PI3K pathway; phosphatidylinositol-3- kinase catalytic subunit alpha as activator (PIK3CA), and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alowiri, Nabil Hadi, Hanafy, Shaden Muawia, Haleem, Reham Abdel, Abdellatif, Ahmed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976819/ https://www.ncbi.nlm.nih.gov/pubmed/31554385 http://dx.doi.org/10.31557/APJCP.2019.20.9.2841

Ejemplares similares

Expression of PIK3CA, PTEN mRNA and PIK3CA mutations in primary breast cancer: association with lymph node metastases
por: Palimaru, Irina, et al.
Publicado: (2013)

The impact of PIK3CA mutations and PTEN expression on the effect of neoadjuvant therapy for postmenopausal luminal breast cancer patients
por: Hayama, Shouko, et al.
Publicado: (2023)

The prognostic role of KRAS, BRAF, PIK3CA and PTEN in colorectal cancer
por: Eklöf, V, et al.
Publicado: (2013)

KRAS, BRAF and PIK3CA Mutations and the Loss of PTEN Expression in Chinese Patients with Colorectal Cancer
por: Mao, Chen, et al.
Publicado: (2012)

PIK3CA amplification and PTEN loss in diffused large B-cell lymphoma
por: Cui, Wenli, et al.
Publicado: (2017)

Aberrant PTEN, PIK3CA, pMAPK, and TP53 expression in human scalp and face angiosarcoma
por: Wan, Huiying, et al.
Publicado: (2021)

PIK3CA-mutations in breast cancer
por: Reinhardt, Kristin, et al.
Publicado: (2022)

PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma
por: Chiosea, Simion I, et al.
Publicado: (2013)

Any Role of PIK3CA and PTEN Biomarkers in the Prognosis in Oral Squamous Cell Carcinoma?
por: Starzyńska, Anna, et al.
Publicado: (2020)

Association of PIK3CA mutation and PTEN loss with expression of CD274 (PD-L1) in colorectal carcinoma
por: Ugai, Tomotaka, et al.
Publicado: (2021)

Prevalence and spectrum of AKT1, PIK3CA, PTEN and TP53 somatic mutations in Chinese breast cancer patients
por: Li, Guoli, et al.
Publicado: (2018)

Mutational Landscape and In-Silico Analysis of TP53, PIK3CA, and PTEN in Patients with Breast Cancer from Khyber Pakhtunkhwa
por: Ahmad, Hilal, et al.
Publicado: (2023)

Common and distinct features of mammary tumors driven by Pten-deletion or activating Pik3ca mutation
por: Liu, Jeff C., et al.
Publicado: (2016)

Pilot investigation of the mutation profile of PIK3CA/PTEN genes (PI3K pathway) in grade 3 endometrial cancer
por: Malentacchi, Francesca, et al.
Publicado: (2019)

Initiating breast cancer by PIK3CA mutation
por: Miller, Todd W
Publicado: (2012)

An Integrative Analysis of PIK3CA Mutation, PTEN, and INPP4B Expression in Terms of Trastuzumab Efficacy in HER2-Positive Breast Cancer
por: Sueta, Aiko, et al.
Publicado: (2014)

Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
por: Pesch, Andrea M., et al.
Publicado: (2022)

Concordant analysis of KRAS, BRAF, PIK3CA mutations, and PTEN expression between primary colorectal cancer and matched metastases
por: Mao, Chen, et al.
Publicado: (2015)

Carcinogenesis of PIK3CA
por: German, Sidra, et al.
Publicado: (2013)

Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN
por: Laes, Jean-François, et al.
Publicado: (2017)

PIK3CA Genotype and a PIK3CA Mutation-Related Gene Signature and Response to Everolimus and Letrozole in Estrogen Receptor Positive Breast Cancer
por: Loi, Sherene, et al.
Publicado: (2013)

Alterations in PTEN and PIK3CA in colorectal cancers in the EPIC Norfolk study: associations with clinicopathological and dietary factors
por: Naguib, Adam, et al.
Publicado: (2011)

EGFR, KRAS, BRAF, PTEN, and PIK3CA mutation in plasma of small cell lung cancer patients
por: Lu, Hong-Yang, et al.
Publicado: (2018)

Liquid biopsy: Novel perspectives on the importance and spectrum of PIK3CA, PTEN and RET mutations in solid tumors
por: Sahin, Ibrahim, et al.
Publicado: (2022)

Prognostic value of the PIK3CA, AKT, and PTEN mutations in oral squamous cell carcinoma: literature review
por: Starzyńska, Anna, et al.
Publicado: (2020)

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
por: Chen, Li, et al.
Publicado: (2018)

Correction: PIK3CA Genotype and a PIK3CA Mutation-Related Gene Signature and Response to Everolimus and Letrozole in Estrogen Receptor Positive Breast Cancer
por: Loi, Sherene, et al.
Publicado: (2019)

PTEN and PIK3CA gene copy numbers and poor outcomes in non-small cell lung cancer patients with gefitinib therapy
por: Fidler, M J, et al.
Publicado: (2011)

Prediction of PIK3CA mutations from cancer gene expression data
por: Kang, Jun, et al.
Publicado: (2020)

Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation
por: Xing, Yan, et al.
Publicado: (2019)

Variable Expression of PIK3R3 and PTEN in Ewing Sarcoma Impacts Oncogenic Phenotypes
por: Niemeyer, Brian F., et al.
Publicado: (2015)

PIK3CA in Colorectal Cancer
por: Cathomas, Gieri
Publicado: (2014)

PIK3CA Gene Amplification and PI3K p110α Protein Expression in Breast Carcinoma
por: Firoozinia, Mohammad, et al.
Publicado: (2014)

The role of the PIK3CA gene in the development and aging of the brain
por: Xie, Shaozhen, et al.
Publicado: (2021)

Helical and kinase domain mutations of PIK3CA, and their association with hormone receptor expression in breast cancer
por: Vatte, Chittibabu, et al.
Publicado: (2019)

Detection of PIK3CA Mutations in Breast Cancer Bone Metastases
por: Daneshmand, Manijeh, et al.
Publicado: (2012)

Frequency and spectrum of PIK3CA somatic mutations in breast cancer
por: Martínez-Sáez, Olga, et al.
Publicado: (2020)

PIK3CA mutations in breast cancer: A Tunisian series
por: Ben Rekaya, Mariem, et al.
Publicado: (2023)

Allelic expression imbalance of PIK3CA mutations is frequent in breast cancer and prognostically significant
por: Correia, Lizelle, et al.
Publicado: (2022)

Correction: Variable Expression of PIK3R3 and PTEN in Ewing Sarcoma Impacts Oncogenic Phenotypes
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_6puai4789f7g9bg85kqe3f7rai