The Association of Dietary Intake of Calcium and Vitamin D to Colorectal Cancer Risk among Iranian Population

BACKGROUND: Vitamin D and Calcium have a possible protective impact versus rectal neoplasm. Vitamin D, an important nutrient, is vital to regulate the absorption of calcium and bone mineralization; nevertheless, in a case-control study in Iran, we investigated the relationship among the dietary inta...

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Detalles Bibliográficos
Autores principales: Hosseinzadeh, Payam, Javanbakht, Mohammad, Alemrajabi, Mahdi, Gholami, Ali, Amirkalali, Bahareh, Sohrabi, Masoudreza, Zamani, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976838/
https://www.ncbi.nlm.nih.gov/pubmed/31554383
http://dx.doi.org/10.31557/APJCP.2019.20.9.2825
Descripción
Sumario:BACKGROUND: Vitamin D and Calcium have a possible protective impact versus rectal neoplasm. Vitamin D, an important nutrient, is vital to regulate the absorption of calcium and bone mineralization; nevertheless, in a case-control study in Iran, we investigated the relationship among the dietary intake of vitamin D and calcium with the hazard of rectal neoplasm. METHODS: 363 subjects (162 cases and 201 controls) participated in the case- control Study from March 2017 to November 2018. Dietary intake of Calcium and Vitamin D was calculated using a 148-items food-frequency questionnaire. RESULTS: Since altering the strong confounding agents, the multivariate risk proportion within the dietary vitamin D intake was OR=0.2, 95%CI 0.1-0.5, P-value <0.001 among cases. There was no association in case of calcium and rectal cancer. CONCLUSIONS: Taken together, a possible reduction in the hazard of rectal neoplasm with dietary intake of Vitamin D within Iranian patients was observed.

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