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Signal Transduction of Improving Effects of Ibudilast on Methamphetamine Induced Cell Death

OBJECTIVE: Interaction of methamphetamine and sigma (σ) receptors lead to up-regulation and activation of these receptors. The σ receptors induced apoptosis in some parts of the brain by increasing calcium, dopamine, ROS, mitochondrial pores and caspase activity. Ibudilast is a phosphodiesterase inh...

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Detalles Bibliográficos
Autores principales:	Tahvilian, Reza, Amini, Komail, Zhaleh, Hossein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976860/ https://www.ncbi.nlm.nih.gov/pubmed/31554375 http://dx.doi.org/10.31557/APJCP.2019.20.9.2763

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