Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20

Enterovirus D68 (EV-D68) was detected in 93 patients from five European countries between 1 January 2019 and 15 January 2020, a season with expected low circulation. Patients were primarily children (n = 67, median age: 4 years), 59 patients required hospitalisation and five had severe neurologic ma...

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Autores principales: Midgley, Sofie Elisabeth, Benschop, Kimberley, Dyrdak, Robert, Mirand, Audrey, Bailly, Jean-Luc, Bierbaum, Sibylle, Buderus, Stefan, Böttcher, Sindy, Eis-Hübinger, Anna-Maria, Hönemann, Mario, Jensen, Veronika Vorobieva, Hartling, Ulla Birgitte, Henquell, Cécile, Panning, Marcus, Thomsen, Marianne Kragh, Hodcroft, Emma B, Meijer, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2020
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976881/
https://www.ncbi.nlm.nih.gov/pubmed/31964463
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.2.1900749
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author Midgley, Sofie Elisabeth
Benschop, Kimberley
Dyrdak, Robert
Mirand, Audrey
Bailly, Jean-Luc
Bierbaum, Sibylle
Buderus, Stefan
Böttcher, Sindy
Eis-Hübinger, Anna-Maria
Hönemann, Mario
Jensen, Veronika Vorobieva
Hartling, Ulla Birgitte
Henquell, Cécile
Panning, Marcus
Thomsen, Marianne Kragh
Hodcroft, Emma B
Meijer, Adam
author_facet Midgley, Sofie Elisabeth
Benschop, Kimberley
Dyrdak, Robert
Mirand, Audrey
Bailly, Jean-Luc
Bierbaum, Sibylle
Buderus, Stefan
Böttcher, Sindy
Eis-Hübinger, Anna-Maria
Hönemann, Mario
Jensen, Veronika Vorobieva
Hartling, Ulla Birgitte
Henquell, Cécile
Panning, Marcus
Thomsen, Marianne Kragh
Hodcroft, Emma B
Meijer, Adam
author_sort Midgley, Sofie Elisabeth
collection PubMed
description Enterovirus D68 (EV-D68) was detected in 93 patients from five European countries between 1 January 2019 and 15 January 2020, a season with expected low circulation. Patients were primarily children (n = 67, median age: 4 years), 59 patients required hospitalisation and five had severe neurologic manifestations. Phylogenetic analysis revealed two clusters in the B3 subclade and subclade A2/D. This circulation of EV-D68 associated with neurological manifestations stresses the importance of surveillance and diagnostics beyond expected peak years.
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spelling pubmed-69768812020-01-31 Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20 Midgley, Sofie Elisabeth Benschop, Kimberley Dyrdak, Robert Mirand, Audrey Bailly, Jean-Luc Bierbaum, Sibylle Buderus, Stefan Böttcher, Sindy Eis-Hübinger, Anna-Maria Hönemann, Mario Jensen, Veronika Vorobieva Hartling, Ulla Birgitte Henquell, Cécile Panning, Marcus Thomsen, Marianne Kragh Hodcroft, Emma B Meijer, Adam Euro Surveill Rapid Communication Enterovirus D68 (EV-D68) was detected in 93 patients from five European countries between 1 January 2019 and 15 January 2020, a season with expected low circulation. Patients were primarily children (n = 67, median age: 4 years), 59 patients required hospitalisation and five had severe neurologic manifestations. Phylogenetic analysis revealed two clusters in the B3 subclade and subclade A2/D. This circulation of EV-D68 associated with neurological manifestations stresses the importance of surveillance and diagnostics beyond expected peak years. European Centre for Disease Prevention and Control (ECDC) 2020-01-16 /pmc/articles/PMC6976881/ /pubmed/31964463 http://dx.doi.org/10.2807/1560-7917.ES.2020.25.2.1900749 Text en This article is copyright of the authors or their affiliated institutions, 2020. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Midgley, Sofie Elisabeth
Benschop, Kimberley
Dyrdak, Robert
Mirand, Audrey
Bailly, Jean-Luc
Bierbaum, Sibylle
Buderus, Stefan
Böttcher, Sindy
Eis-Hübinger, Anna-Maria
Hönemann, Mario
Jensen, Veronika Vorobieva
Hartling, Ulla Birgitte
Henquell, Cécile
Panning, Marcus
Thomsen, Marianne Kragh
Hodcroft, Emma B
Meijer, Adam
Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20
title Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20
title_full Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20
title_fullStr Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20
title_full_unstemmed Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20
title_short Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20
title_sort co-circulation of multiple enterovirus d68 subclades, including a novel b3 cluster, across europe in a season of expected low prevalence, 2019/20
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976881/
https://www.ncbi.nlm.nih.gov/pubmed/31964463
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.2.1900749
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