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Long non-coding RNA X-inactive specific transcript silencing ameliorates primary graft dysfunction following lung transplantation through microRNA-21-dependent mechanism

BACKGROUND: Primary graft dysfunction (PGD) is a known acute lung injury (ALI) and a major cause of fatality post-lung transplantation. Though some long non-coding RNAs (lncRNAs) have been studied in ALI through regulation of microRNAs (miRNAs), their effects on PGD remain undefined. The present stu...

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Detalles Bibliográficos
Autores principales: Li, Jiwei, Wei, Li, Han, Zhijun, Chen, Zhong, Zhang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976928/
https://www.ncbi.nlm.nih.gov/pubmed/31981974
http://dx.doi.org/10.1016/j.ebiom.2019.102600