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Effect of ER stress on sphingolipid levels and apoptotic pathways in retinal pigment epithelial cells

BACKGROUND: We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. METHODS: Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER st...

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Detalles Bibliográficos
Autores principales:	Afşar, Ebru, Kırımlıoglu, Esma, Çeker, Tuğçe, Yılmaz, Çağatay, Demir, Necdet, Aslan, Mutay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976939/ https://www.ncbi.nlm.nih.gov/pubmed/31978676 http://dx.doi.org/10.1016/j.redox.2020.101430

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