Cargando…

Impact of obese levels on the hepatic expression of nuclear receptors and drug-metabolizing enzymes in adult and offspring mice

The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs) has been shown in obesity, the impacts of obese levels (overweight, obesity, and severe obesity) on the expression of DMEs have not been eluci...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Pei, Shao, Xueyan, Bao, Yifan, Zhu, Junjie, Chen, Liming, Zhang, Lirong, Ma, Xiaochao, Zhong, Xiao-bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976990/
https://www.ncbi.nlm.nih.gov/pubmed/31993314
http://dx.doi.org/10.1016/j.apsb.2019.10.009