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Impact of obese levels on the hepatic expression of nuclear receptors and drug-metabolizing enzymes in adult and offspring mice
The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs) has been shown in obesity, the impacts of obese levels (overweight, obesity, and severe obesity) on the expression of DMEs have not been eluci...
Autores principales: | Wang, Pei, Shao, Xueyan, Bao, Yifan, Zhu, Junjie, Chen, Liming, Zhang, Lirong, Ma, Xiaochao, Zhong, Xiao-bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976990/ https://www.ncbi.nlm.nih.gov/pubmed/31993314 http://dx.doi.org/10.1016/j.apsb.2019.10.009 |
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