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Impact of obese levels on the hepatic expression of nuclear receptors and drug-metabolizing enzymes in adult and offspring mice

The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs) has been shown in obesity, the impacts of obese levels (overweight, obesity, and severe obesity) on the expression of DMEs have not been eluci...

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Detalles Bibliográficos
Autores principales: Wang, Pei, Shao, Xueyan, Bao, Yifan, Zhu, Junjie, Chen, Liming, Zhang, Lirong, Ma, Xiaochao, Zhong, Xiao-bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976990/
https://www.ncbi.nlm.nih.gov/pubmed/31993314
http://dx.doi.org/10.1016/j.apsb.2019.10.009

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