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pPerturb: A Server for Predicting Long-Distance Energetic Couplings and Mutation-Induced Stability Changes in Proteins via Perturbations

[Image: see text] The strength of intraprotein interactions or contact network is one of the dominant factors determining the thermodynamic stabilities of proteins. The nature and the extent of connectivity of this network also play a role in allosteric signal propagation characteristics upon ligand...

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Detalles Bibliográficos
Autores principales: Gopi, Soundhararajan, Devanshu, Devanshu, Rajasekaran, Nandakumar, Anantakrishnan, Sathvik, Naganathan, Athi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977024/
https://www.ncbi.nlm.nih.gov/pubmed/31984271
http://dx.doi.org/10.1021/acsomega.9b03371