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pPerturb: A Server for Predicting Long-Distance Energetic Couplings and Mutation-Induced Stability Changes in Proteins via Perturbations
[Image: see text] The strength of intraprotein interactions or contact network is one of the dominant factors determining the thermodynamic stabilities of proteins. The nature and the extent of connectivity of this network also play a role in allosteric signal propagation characteristics upon ligand...
Autores principales: | Gopi, Soundhararajan, Devanshu, Devanshu, Rajasekaran, Nandakumar, Anantakrishnan, Sathvik, Naganathan, Athi N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977024/ https://www.ncbi.nlm.nih.gov/pubmed/31984271 http://dx.doi.org/10.1021/acsomega.9b03371 |
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