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Design and Characterization of Cyclosporine A-Loaded Nanofibers for Enhanced Drug Dissolution
[Image: see text] Despite widespread use as an immunosuppressant, the therapeutic efficacy of the undecapeptide cyclosporine A (CyA) is compromised when given by the oral route because of the innate hydrophobicity of the drug molecule, potentially leading to poor aqueous solubility and bioavailabili...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977102/ https://www.ncbi.nlm.nih.gov/pubmed/31984256 http://dx.doi.org/10.1021/acsomega.9b02616 |