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Design and Characterization of Cyclosporine A-Loaded Nanofibers for Enhanced Drug Dissolution

[Image: see text] Despite widespread use as an immunosuppressant, the therapeutic efficacy of the undecapeptide cyclosporine A (CyA) is compromised when given by the oral route because of the innate hydrophobicity of the drug molecule, potentially leading to poor aqueous solubility and bioavailabili...

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Detalles Bibliográficos
Autores principales: Dubey, Poornima, Barker, Susan A., Craig, Duncan Q. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977102/
https://www.ncbi.nlm.nih.gov/pubmed/31984256
http://dx.doi.org/10.1021/acsomega.9b02616

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