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Preclinical Development and Assessment of Viral Vectors Expressing a Fusion Antigen of Plasmodium falciparum LSA1 and LSAP2 for Efficacy against Liver-Stage Malaria

Despite promising progress in malaria vaccine development in recent years, an efficacious subunit vaccine against Plasmodium falciparum remains to be licensed and deployed. Cell-mediated protection from liver-stage malaria relies on a sufficient number of antigen-specific T cells reaching the liver...

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Detalles Bibliográficos
Autores principales: Halbroth, Benedict R., Sebastian, Sarah, Salman, Ahmed M., Ulaszewska, Marta, Gola, Anita, Longley, Rhea J., Janse, Chris J., Khan, Shahid M., Hill, Adrian V. S., Spencer, Alexandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977128/
https://www.ncbi.nlm.nih.gov/pubmed/31740525
http://dx.doi.org/10.1128/IAI.00573-19