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Tailor-made solvents for pharmaceutical use? Experimental and computational approach for determining solubility in deep eutectic solvents (DES)
A deep eutectic solvent (DES) is a mixture of two or more chemicals that interact via hydrogen bonding and has a melting point far below that of the individual components. DESs have been proposed as alternative solvents for poorly soluble active pharmaceutical ingredients (API). In this study, the s...
Autores principales: | Palmelund, Henrik, Andersson, Martin P., Asgreen, Camilla J., Boyd, Ben J., Rantanen, Jukka, Löbmann, Korbinian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977171/ https://www.ncbi.nlm.nih.gov/pubmed/31993583 http://dx.doi.org/10.1016/j.ijpx.2019.100034 |
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