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Vaspin antagonizes high fat-induced bone loss in rats and promotes osteoblastic differentiation in primary rat osteoblasts through Smad-Runx2 signaling pathway
BACKGROUND: Visceral adipose tissue-derived serine protease inhibitor (vaspin), an adipose-derived hormone, exhibits various biological functions. Recently, studies showed that vaspin is closely related to bone metabolism. However, how vaspin influences bone formation and its underlying mechanisms i...
Autores principales: | Wang, Hongwei, Chen, Fulian, Li, Jiaxuan, Wang, Yan, Jiang, Chunyan, Zhang, Mengqi, Xu, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977231/ https://www.ncbi.nlm.nih.gov/pubmed/31993071 http://dx.doi.org/10.1186/s12986-020-0429-5 |
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