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A two-pore channel protein required for regulating mTORC1 activity on starvation
BACKGROUND: Two-pore channels (TPCs) release Ca(2+) from acidic intracellular stores and are implicated in a number of diseases, but their role in development is unclear. The social amoeba Dictyostelium discoideum proliferates as single cells that aggregate to form a multicellular organism on starva...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977259/ https://www.ncbi.nlm.nih.gov/pubmed/31969153 http://dx.doi.org/10.1186/s12915-019-0735-4 |