Metallohelices that kill Gram-negative pathogens using intracellular antimicrobial peptide pathways

A range of new water-compatible optically pure metallohelices – made by self-assembly of simple non-peptidic organic components around Fe ions – exhibit similar architecture to some natural cationic antimicrobial peptides (CAMPs) and are found to have high, structure-dependent activity against bacte...

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Detalles Bibliográficos
Autores principales: Simpson, Daniel H., Hapeshi, Alexia, Rogers, Nicola J., Brabec, Viktor, Clarkson, Guy J., Fox, David J., Hrabina, Ondrej, Kay, Gemma L., King, Andrew K., Malina, Jaroslav, Millard, Andrew D., Moat, John, Roper, David I., Song, Hualong, Waterfield, Nicholas R., Scott, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977464/
https://www.ncbi.nlm.nih.gov/pubmed/32015803
http://dx.doi.org/10.1039/c9sc03532j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977464/
https://www.ncbi.nlm.nih.gov/pubmed/32015803
http://dx.doi.org/10.1039/c9sc03532j

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