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Dexmedetomidine Post-Conditioning Alleviates Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting High Mobility Group Protein B1 Group (HMGB1)/Toll-Like Receptor 4 (TLR4)/Nuclear Factor kappa B (NF-κB) Signaling Pathway

BACKGROUND: Cerebral ischemia-reperfusion injury is a pivotal cause of deaths due to cerebrovascular accident. Increased research efforts are needed to reveal the mechanism underlying its aggravation or alleviation. In this study, the effects of dexmedetomidine post-conditioning on the HMGB1/TLR4/NF...

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Detalles Bibliográficos
Autores principales: Zhai, Yongyi, Zhu, Yulin, Liu, Jingying, Xie, Kun, Yu, Jingui, Yu, Lingzhi, Deng, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977611/
https://www.ncbi.nlm.nih.gov/pubmed/31912804
http://dx.doi.org/10.12659/MSM.918617