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Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein

Alzheimer’s disease (AD) is the most prevalent type of dementia. Down syndrome (DS) is the leading genetic risk factor for Early-Onset AD, prematurely presenting the classic pathological features of the brain with AD. Augmented gene dosage, including the APP gene, could partially cause this predispo...

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Detalles Bibliográficos
Autores principales:	Gomez, Wileidy, Morales, Rodrigo, Maracaja-Coutinho, Vinicius, Parra, Valentina, Nassif, Melissa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977673/ https://www.ncbi.nlm.nih.gov/pubmed/31918411 http://dx.doi.org/10.18632/aging.102677

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