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Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer

Lycorine is a powerful anti-cancer agent against various cancer cell lines with minor side effects. However, the detailed mechanisms of its effects in colorectal cancer (CRC) remain unclear. In this study, we investigated the function and mechanism of lycorine against CRC both in vitro and in vivo....

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Detalles Bibliográficos
Autores principales: Hu, Man, Yu, Zhaomin, Mei, Peiyuan, Li, Jinxiao, Luo, Dan, Zhang, Haiming, Zhou, Minfeng, Liang, Fengxia, Chen, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977686/
https://www.ncbi.nlm.nih.gov/pubmed/31901897
http://dx.doi.org/10.18632/aging.102606