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Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer
Lycorine is a powerful anti-cancer agent against various cancer cell lines with minor side effects. However, the detailed mechanisms of its effects in colorectal cancer (CRC) remain unclear. In this study, we investigated the function and mechanism of lycorine against CRC both in vitro and in vivo....
Autores principales: | Hu, Man, Yu, Zhaomin, Mei, Peiyuan, Li, Jinxiao, Luo, Dan, Zhang, Haiming, Zhou, Minfeng, Liang, Fengxia, Chen, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977686/ https://www.ncbi.nlm.nih.gov/pubmed/31901897 http://dx.doi.org/10.18632/aging.102606 |
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