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Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter
Cisplatin is one of the most potent chemotherapeutic agents for the treatment of colon cancer. Nevertheless, the unavoidability of the notable toxicity and the development of the acquired resistance severely restricted its clinical application. Aspirin and some other non-steroidal anti-inflammatory...
Autores principales: | Jiang, Wei, Yan, Yue, Chen, Manyu, Luo, Guangyu, Hao, Jiaojiao, Pan, Jinjin, Hu, Sheng, Guo, Ping, Li, Wenyang, Wang, Ruozu, Zuo, Yan, Sun, Yao, Sui, Silei, Yu, Wendan, Pan, Zhe, Zou, Kun, Zheng, Zongheng, Deng, Wuguo, Wu, Xiaojun, Guo, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977689/ https://www.ncbi.nlm.nih.gov/pubmed/31905343 http://dx.doi.org/10.18632/aging.102644 |
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