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Changes in sleep duration and 3-year risk of mild cognitive impairment in Chinese older adults

Objective: This study aimed to determine whether changes in sleep duration are associated with a higher risk of mild cognitive impairment (MCI) in older adults. Results: By the 3-year follow-up, 592 participants developed MCI. Compared with the individuals who had an unchanged sleep duration, the od...

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Detalles Bibliográficos
Autores principales: Zhu, Qi, Fan, Hui, Zhang, Xiaoning, Ji, Chao, Xia, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977705/
https://www.ncbi.nlm.nih.gov/pubmed/31899685
http://dx.doi.org/10.18632/aging.102616
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author Zhu, Qi
Fan, Hui
Zhang, Xiaoning
Ji, Chao
Xia, Yang
author_facet Zhu, Qi
Fan, Hui
Zhang, Xiaoning
Ji, Chao
Xia, Yang
author_sort Zhu, Qi
collection PubMed
description Objective: This study aimed to determine whether changes in sleep duration are associated with a higher risk of mild cognitive impairment (MCI) in older adults. Results: By the 3-year follow-up, 592 participants developed MCI. Compared with the individuals who had an unchanged sleep duration, the odds ratio (95% confidence interval) for MCI was 1.44 (1.08-1.91) for those whose sleep duration increased by ≥2 h after multivariate adjustments. Moreover, changing from a long to moderate, but not short, sleep duration was negatively associated with the incidence of MCI (odds ratio: 0.65; 95% confidence interval, 0.45-0.93). Conclusions: These findings suggest that increased sleep duration is associated with a higher risk of MCI in the elderly. Furthermore, a moderate duration of sleep (6-9 h) could serve as a possible strategy for prevention of MCI. Methods: This longitudinal study was conducted with a nationally representative sample of 5419 older Chinese adults (≥65 years) from the 2008 and 2011 waves of the Chinese Longitudinal Healthy Longevity Survey. Sleep duration was assessed by a self-administered questionnaire. MCI was defined according to the Mini-Mental State Examination. An adjusted logistic regression model was used to explore the associations between changes in sleep duration and MCI.
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spelling pubmed-69777052020-01-31 Changes in sleep duration and 3-year risk of mild cognitive impairment in Chinese older adults Zhu, Qi Fan, Hui Zhang, Xiaoning Ji, Chao Xia, Yang Aging (Albany NY) Research Paper Objective: This study aimed to determine whether changes in sleep duration are associated with a higher risk of mild cognitive impairment (MCI) in older adults. Results: By the 3-year follow-up, 592 participants developed MCI. Compared with the individuals who had an unchanged sleep duration, the odds ratio (95% confidence interval) for MCI was 1.44 (1.08-1.91) for those whose sleep duration increased by ≥2 h after multivariate adjustments. Moreover, changing from a long to moderate, but not short, sleep duration was negatively associated with the incidence of MCI (odds ratio: 0.65; 95% confidence interval, 0.45-0.93). Conclusions: These findings suggest that increased sleep duration is associated with a higher risk of MCI in the elderly. Furthermore, a moderate duration of sleep (6-9 h) could serve as a possible strategy for prevention of MCI. Methods: This longitudinal study was conducted with a nationally representative sample of 5419 older Chinese adults (≥65 years) from the 2008 and 2011 waves of the Chinese Longitudinal Healthy Longevity Survey. Sleep duration was assessed by a self-administered questionnaire. MCI was defined according to the Mini-Mental State Examination. An adjusted logistic regression model was used to explore the associations between changes in sleep duration and MCI. Impact Journals 2020-01-03 /pmc/articles/PMC6977705/ /pubmed/31899685 http://dx.doi.org/10.18632/aging.102616 Text en Copyright © 2020 Zhu et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Paper
Zhu, Qi
Fan, Hui
Zhang, Xiaoning
Ji, Chao
Xia, Yang
Changes in sleep duration and 3-year risk of mild cognitive impairment in Chinese older adults
title Changes in sleep duration and 3-year risk of mild cognitive impairment in Chinese older adults
title_full Changes in sleep duration and 3-year risk of mild cognitive impairment in Chinese older adults
title_fullStr Changes in sleep duration and 3-year risk of mild cognitive impairment in Chinese older adults
title_full_unstemmed Changes in sleep duration and 3-year risk of mild cognitive impairment in Chinese older adults
title_short Changes in sleep duration and 3-year risk of mild cognitive impairment in Chinese older adults
title_sort changes in sleep duration and 3-year risk of mild cognitive impairment in chinese older adults
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977705/
https://www.ncbi.nlm.nih.gov/pubmed/31899685
http://dx.doi.org/10.18632/aging.102616
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