Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo

Besides monocyte (MO)-derived macrophages (MACs), self-renewing tissue-resident macrophages (trMACs) maintain the intracutaneous MAC pool in murine skin. Here, we have asked whether the same phenomenon occurs in human skin using organ-cultured, full-thickness skin detached from blood circulation and...

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Detalles Bibliográficos
Autores principales: Gherardini, Jennifer, Uchida, Youhei, Hardman, Jonathan A., Chéret, Jérémy, Mace, Kimberly, Bertolini, Marta, Paus, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977738/
https://www.ncbi.nlm.nih.gov/pubmed/31971954
http://dx.doi.org/10.1371/journal.pone.0227817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977738/
https://www.ncbi.nlm.nih.gov/pubmed/31971954
http://dx.doi.org/10.1371/journal.pone.0227817

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