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Mutant Frequency is not Increased in Mice Orally Exposed to Sodium Dichromate
The in vivo mutagenicity of hexavalent chromium in the small intestine, the target organ of tumorgenicity, was examined by means of a transgenic mouse gene mutation assay. Sodium dichromate dihydrate was administered orally in drinking water to male gpt delta mice at a dose of 85.7 or 257.4 mg/L for...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Food Safety Commission, Cabinet Office, Government of Japan
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977768/ https://www.ncbi.nlm.nih.gov/pubmed/31998582 http://dx.doi.org/10.14252/foodsafetyfscj.2018014 |