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Mutant Frequency is not Increased in Mice Orally Exposed to Sodium Dichromate

The in vivo mutagenicity of hexavalent chromium in the small intestine, the target organ of tumorgenicity, was examined by means of a transgenic mouse gene mutation assay. Sodium dichromate dihydrate was administered orally in drinking water to male gpt delta mice at a dose of 85.7 or 257.4 mg/L for...

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Detalles Bibliográficos
Autores principales: Aoki, Yasunobu, Matsumoto, Michiyo, Matsumoto, Michi, Masumura, Kenichi, Nohmi, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Food Safety Commission, Cabinet Office, Government of Japan 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977768/
https://www.ncbi.nlm.nih.gov/pubmed/31998582
http://dx.doi.org/10.14252/foodsafetyfscj.2018014

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