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Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV

Establishment of viral latency is not only essential for lifelong Kaposi’s sarcoma-associated herpesvirus (KSHV) infection, but it is also a prerequisite of viral tumorigenesis. The latent viral DNA has a complex chromatin structure, which is established in a stepwise manner regulated by host epigen...

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Detalles Bibliográficos
Autores principales: Naik, Nenavath Gopal, Nguyen, Thomas Hong, Roberts, Lauren, Fischer, Luke Todd, Glickman, Katherine, Golas, Gavin, Papp, Bernadett, Toth, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977772/
https://www.ncbi.nlm.nih.gov/pubmed/31923286
http://dx.doi.org/10.1371/journal.ppat.1008268