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Genetic Variability of the AcrAB-TolC Multidrug Efflux Pump Underlies SkQ1 Resistance in Gram-Negative Bacteria
SkQ1, a novel antibiotic targeting bacterial bioenergetics, is highly effective against both gram-positive and gram-negative bacteria. However, some gram-negative bacteria, such as Escherichia coli and Klebsiella pneumoniae, are highly resistant to it. In different gram-negative bacteria, this resis...
Autores principales: | Nazarov, P. A., Kotova, E. A., Skulachev, V. P., Antonenko, Y. N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
A.I. Gordeyev
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977953/ https://www.ncbi.nlm.nih.gov/pubmed/31993240 http://dx.doi.org/10.32607/20758251-2019-11-4-93-98 |
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