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Genetic Variability of the AcrAB-TolC Multidrug Efflux Pump Underlies SkQ1 Resistance in Gram-Negative Bacteria

SkQ1, a novel antibiotic targeting bacterial bioenergetics, is highly effective against both gram-positive and gram-negative bacteria. However, some gram-negative bacteria, such as Escherichia coli and Klebsiella pneumoniae, are highly resistant to it. In different gram-negative bacteria, this resis...

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Detalles Bibliográficos
Autores principales: Nazarov, P. A., Kotova, E. A., Skulachev, V. P., Antonenko, Y. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977953/
https://www.ncbi.nlm.nih.gov/pubmed/31993240
http://dx.doi.org/10.32607/20758251-2019-11-4-93-98

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