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Effect of Spironolactone on Atrial Fibrillation in Patients with Heart Failure with Preserved Ejection Fraction: Post-Hoc Analysis of the Randomized, Placebo-Controlled TOPCAT Trial
BACKGROUND: Mineralocorticoid receptor antagonists (MRAs) reduce the risk of atrial fibrillation (AF) in patients with heart failure (HF) and a reduced ejection fraction. The efficacy of MRAs for AF prevention in patients with HF and a preserved ejection fraction (HFpEF) is unclear. OBJECTIVES: We p...
Autores principales: | Neefs, Jolien, van den Berg, Nicoline W. E., Krul, Sébastien P. J., Boekholdt, S. Matthijs, de Groot, Joris R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978290/ https://www.ncbi.nlm.nih.gov/pubmed/31214914 http://dx.doi.org/10.1007/s40256-019-00353-5 |
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