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A facile and efficient method for the synthesis of crystalline tetrahydro-β-carbolines via the Pictet-Spengler reaction in water

A facile and efficient synthesis of tetrahydro-β-carbolines (tryptolines) in one step from tryptamine and aldehydes, in an environmentally friendly water solvent, has been investigated. This convenient and clean synthesis of various tryptolines was facilitated by l-tartaric acid, a natural compound,...

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Detalles Bibliográficos
Autores principales:	Byeon, Hong-Ju, Jung, Kyung-Hwan, Moon, Gi-Seong, Moon, Sung-Kwon, Lee, Hyang-Yeol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978303/ https://www.ncbi.nlm.nih.gov/pubmed/31974432 http://dx.doi.org/10.1038/s41598-020-57911-0

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