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The dual role of curcumin and ferulic acid in counteracting chemoresistance and cisplatin-induced ototoxicity

Platinum-based agents, such as cisplatin, form the mainstay of currently used chemotherapeutic regimens for several malignancies; however, the main limitations are chemoresistance and ototoxic side effects. In this study we used two different polyphenols, curcumin and ferulic acid as adjuvant chemot...

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Detalles Bibliográficos
Autores principales: Paciello, Fabiola, Rita Fetoni, Anna, Mezzogori, Daniele, Rolesi, Rolando, Di Pino, Antonella, Paludetti, Gaetano, Grassi, Claudio, Troiani, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978317/
https://www.ncbi.nlm.nih.gov/pubmed/31974389
http://dx.doi.org/10.1038/s41598-020-57965-0