Cargando…

Semantic Segmentation of the Choroid in Swept Source Optical Coherence Tomography Images for Volumetrics

The choroid is a complex vascular tissue that is covered with the retinal pigment epithelium. Ultra high speed swept source optical coherence tomography (SS-OCT) provides us with high-resolution cube scan images of the choroid. Robust segmentation techniques are required to reconstruct choroidal vol...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsuji, Shingo, Sekiryu, Tetsuju, Sugano, Yukinori, Ojima, Akira, Kasai, Akihito, Okamoto, Masahiro, Eifuku, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978344/
https://www.ncbi.nlm.nih.gov/pubmed/31974487
http://dx.doi.org/10.1038/s41598-020-57788-z
_version_ 1783490678505865216
author Tsuji, Shingo
Sekiryu, Tetsuju
Sugano, Yukinori
Ojima, Akira
Kasai, Akihito
Okamoto, Masahiro
Eifuku, Satoshi
author_facet Tsuji, Shingo
Sekiryu, Tetsuju
Sugano, Yukinori
Ojima, Akira
Kasai, Akihito
Okamoto, Masahiro
Eifuku, Satoshi
author_sort Tsuji, Shingo
collection PubMed
description The choroid is a complex vascular tissue that is covered with the retinal pigment epithelium. Ultra high speed swept source optical coherence tomography (SS-OCT) provides us with high-resolution cube scan images of the choroid. Robust segmentation techniques are required to reconstruct choroidal volume using SS-OCT images. For automated segmentation, the delineation of the choroidal-scleral (C-S) boundary is key to accurate segmentation. Low contrast of the boundary, scleral canals formed by the vessel and the nerve, and the posterior stromal layer, may cause segmentation errors. Semantic segmentation is one of the applications of deep learning used to classify the parts of images related to the meanings of the subjects. We applied semantic segmentation to choroidal segmentation and measured the volume of the choroid. The measurement results were validated through comparison with those of other segmentation methods. As a result, semantic segmentation was able to segment the C-S boundary and choroidal volume adequately.
format Online
Article
Text
id pubmed-6978344
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-69783442020-01-30 Semantic Segmentation of the Choroid in Swept Source Optical Coherence Tomography Images for Volumetrics Tsuji, Shingo Sekiryu, Tetsuju Sugano, Yukinori Ojima, Akira Kasai, Akihito Okamoto, Masahiro Eifuku, Satoshi Sci Rep Article The choroid is a complex vascular tissue that is covered with the retinal pigment epithelium. Ultra high speed swept source optical coherence tomography (SS-OCT) provides us with high-resolution cube scan images of the choroid. Robust segmentation techniques are required to reconstruct choroidal volume using SS-OCT images. For automated segmentation, the delineation of the choroidal-scleral (C-S) boundary is key to accurate segmentation. Low contrast of the boundary, scleral canals formed by the vessel and the nerve, and the posterior stromal layer, may cause segmentation errors. Semantic segmentation is one of the applications of deep learning used to classify the parts of images related to the meanings of the subjects. We applied semantic segmentation to choroidal segmentation and measured the volume of the choroid. The measurement results were validated through comparison with those of other segmentation methods. As a result, semantic segmentation was able to segment the C-S boundary and choroidal volume adequately. Nature Publishing Group UK 2020-01-23 /pmc/articles/PMC6978344/ /pubmed/31974487 http://dx.doi.org/10.1038/s41598-020-57788-z Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Tsuji, Shingo
Sekiryu, Tetsuju
Sugano, Yukinori
Ojima, Akira
Kasai, Akihito
Okamoto, Masahiro
Eifuku, Satoshi
Semantic Segmentation of the Choroid in Swept Source Optical Coherence Tomography Images for Volumetrics
title Semantic Segmentation of the Choroid in Swept Source Optical Coherence Tomography Images for Volumetrics
title_full Semantic Segmentation of the Choroid in Swept Source Optical Coherence Tomography Images for Volumetrics
title_fullStr Semantic Segmentation of the Choroid in Swept Source Optical Coherence Tomography Images for Volumetrics
title_full_unstemmed Semantic Segmentation of the Choroid in Swept Source Optical Coherence Tomography Images for Volumetrics
title_short Semantic Segmentation of the Choroid in Swept Source Optical Coherence Tomography Images for Volumetrics
title_sort semantic segmentation of the choroid in swept source optical coherence tomography images for volumetrics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978344/
https://www.ncbi.nlm.nih.gov/pubmed/31974487
http://dx.doi.org/10.1038/s41598-020-57788-z
work_keys_str_mv AT tsujishingo semanticsegmentationofthechoroidinsweptsourceopticalcoherencetomographyimagesforvolumetrics
AT sekiryutetsuju semanticsegmentationofthechoroidinsweptsourceopticalcoherencetomographyimagesforvolumetrics
AT suganoyukinori semanticsegmentationofthechoroidinsweptsourceopticalcoherencetomographyimagesforvolumetrics
AT ojimaakira semanticsegmentationofthechoroidinsweptsourceopticalcoherencetomographyimagesforvolumetrics
AT kasaiakihito semanticsegmentationofthechoroidinsweptsourceopticalcoherencetomographyimagesforvolumetrics
AT okamotomasahiro semanticsegmentationofthechoroidinsweptsourceopticalcoherencetomographyimagesforvolumetrics
AT eifukusatoshi semanticsegmentationofthechoroidinsweptsourceopticalcoherencetomographyimagesforvolumetrics