The C. difficile toxin B membrane translocation machinery is an evolutionarily conserved protein delivery apparatus

Large Clostridial Toxins (LCTs) are a family of six homologous protein toxins that are implicated in severe disease. LCTs infiltrate host cells using a translocation domain (LCT-T) that contains both cell-surface receptor binding sites and a membrane translocation apparatus. Despite much effort, LCT...

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Detalles Bibliográficos
Autores principales: Orrell, Kathleen E., Mansfield, Michael J., Doxey, Andrew C., Melnyk, Roman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978384/
https://www.ncbi.nlm.nih.gov/pubmed/31974369
http://dx.doi.org/10.1038/s41467-020-14306-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978384/
https://www.ncbi.nlm.nih.gov/pubmed/31974369
http://dx.doi.org/10.1038/s41467-020-14306-z

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