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The C. difficile toxin B membrane translocation machinery is an evolutionarily conserved protein delivery apparatus
Large Clostridial Toxins (LCTs) are a family of six homologous protein toxins that are implicated in severe disease. LCTs infiltrate host cells using a translocation domain (LCT-T) that contains both cell-surface receptor binding sites and a membrane translocation apparatus. Despite much effort, LCT...
Autores principales: | Orrell, Kathleen E., Mansfield, Michael J., Doxey, Andrew C., Melnyk, Roman A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978384/ https://www.ncbi.nlm.nih.gov/pubmed/31974369 http://dx.doi.org/10.1038/s41467-020-14306-z |
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