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Inhibitory effect of alpinetin on IL‐6 expression by promoting cytosine methylation in CpG islands in the IL‐6 promoter region

BACKGROUND: Alpinetin is a flavonoid which exerts antibacterial and anti‐inflammatory functions. In order to prove that the induced methylation is an important mechanism for alpinetin in regulating the expression of inflammatory factor Interleukin‐6 (IL‐6), we detected the dinucleotide methylation s...

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Detalles Bibliográficos
Autores principales: Hu, Ke, Li, Yuxian, Liang, Minghua, Liu, Lijing, Chen, Yuefu, Huang, Minjiang, Tan, Bifeng, Luo, Yingquan, Yin, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978396/
https://www.ncbi.nlm.nih.gov/pubmed/31724331
http://dx.doi.org/10.1002/mgg3.993