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The significance of genetic mutations and their prognostic impact on patients with incidental finding of isolated del(20q) in bone marrow without morphologic evidence of a myeloid neoplasm

Patients with a sole del(20q) chromosomal abnormality and without morphologic features of a myeloid neoplasm (MN) have shown variable clinical outcomes. To explore the potential risk stratification markers in this group of patients, we evaluated their genetic mutational landscape by a 35-gene MN-foc...

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Detalles Bibliográficos
Autores principales: Ravindran, Aishwarya, He, Rong, Ketterling, Rhett P., Jawad, Majd D., Chen, Dong, Oliveira, Jennifer L., Nguyen, Phuong L., Viswanatha, David S., Reichard, Kaaren K., Hoyer, James D., Go, Ronald S., Shi, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978416/
https://www.ncbi.nlm.nih.gov/pubmed/31974359
http://dx.doi.org/10.1038/s41408-020-0275-8